Tuesday, July 1, 2008

[StemCells] Marrow, Alzheimer's, Vascular Regeneration

Study in other fields leading to Alzheimer's breakthroughs
05:34 PM CDT on Monday, June 30, 2008

By WENDY RIGBY
KENS-TV

In a lab at the University of Texas at San Antonio, scientists are re-
examining an old disease in a new way.

Instead of focusing on the consequences of Alzheimer's, these
scientists are studying its causes in hopes of finding a way to
prevent the onset.

The disease robs people of their memories and ability to function,
and slowly kills them in what should be their golden years.

"Alzheimer's not only affects the patient, but affects families,
affects society and billions and billions of dollars cost for, you
know, economy," UTSA researcher Dr. Gjumrackch Aliev said.

Aliev says knowledge in the cardiovascular field is transferring to
breakthroughs in Alzheimer's.

Animals are bred to develop neurodegenerative problems with age. Then
after being given an oral antioxidant therapy to help with ischemia
— a decrease in blood supply — their brain function
improved.

"We're able to not only repair structural lesions in the brain, but
memory is returned back to normal and also, animals live much
longer," Aliev said.

Other preliminary works show that in animal models, stem cells
derived from bone marrow may serve as a novel tool for brain vascular
regeneration, providing doctors with yet another avenue to help
repair damage that's already been caused in people with Alzheimer's.

Aliev believes science is on the cusp of some very important
developments in attacking this costly disease.

New discoveries for the treatment of Alzheimer's could well be
related to better therapies for other vascular diseases, like
atherosclerosis, strokes and coronary artery disease.

http://www.kvue.com/news/state/stories/063008kvuealzheimersresearch-
cb.d9aba6c.html

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StemCells subscribers may also be interested in these sites:

Children's Neurobiological Solutions
http://www.CNSfoundation.org/

Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123

The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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