American, British scientists win 2007 Nobel Medicine Prize
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Two Americans and a Briton won the 2007 Nobel Medicine Prize on
Monday for their work in embryonic stem cell research, the Nobel jury
said.(Xinhua Photo)
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Two Americans and a Briton won the 2007 Nobel Medicine Prize on
Monday for their work in embryonic stem cell research, the Nobel jury
said. (Xinhua Photo)
Photo Gallery>>>
STOCKHOLM, Oct. 8 (Xinhua) -- Two Americans and a Briton picked
up the 2007 Nobel Medicine Prize Monday for their work in embryonic
stem cell research, the Nobel jury said.
Briton Martin J. Evans and Americans Mario R. Capecchi and Oliver
Smithies shared the Medicine Prize for their "groundbreaking
discoveries concerning embryonic stem cells and DNA recombination in
mammals," according to the Nobel jury at the Karolinska Institute.
The international team has made significant contributions to
introducing genetic changes in mice using embryonic stem cells.
The process has been used to determine why some diseases strike
people at a cellular level, as well as models in mice that show how
human disorders such as cardiovascular ailments, diabetes and cancer
exist and strike otherwise healthy people.
Capecchi, 70, was born in Italy but has become a U.S. citizen.
Capecchi's research has uncovered the roles of genes involved in
mammalian organ development and in the establishment of the body
plan, the award committee said.
Both Evans, 66, and Smithies, 82, are British-born although the
latter holds U.S. citizenship.
Evans applied gene targeting to develop mouse models for human
diseases, and has used these models to study disease mechanisms and
to test the effects of gene therapy.
And Smithies, a professor at the University of North Carolina at
Chapel Hill, also used gene targeting to develop mouse models for
inherited diseases including cystic fibrosis and the blood disease
thalassemia.
The award committee praised their work for having helped expand
the knowledge of "numerous genes in embryonic development, adult
physiology, aging and disease."
The medicine prize was the first of the six prestigious awards to
be announced this year.
The winners of the Physics Prize will be announced Tuesday, to be
followed by those for Chemistry Wednesday, Literature Thursday, Peace
Friday and Economics next Monday.
Last year, the Nobel Prize for medicine went to Americans Andrew
Z. Fire and Craig C. Mello for their work in controlling the flow of
genetic information.
The annual Nobel Prizes are usually announced in October and are
handed out on Dec. 10, the anniversary of the 1896 death of Alfred
Nobel, a Swedish industrialist and the inventor of dynamite.
Nobel died childless and dedicated his vast fortune to
create "prizes for those, who, during the preceding year, shall have
conferred the greatest benefit on mankind."
The prizes have been awarded since 1901. Each prize consists of a
medal, a personal diploma and a cash award of 10 million Swedish
kronor (1.53 million U.S. dollars).
http://news.
Sweden: Italo-American among 2007 Nobel Prize for Medicine trio
Stockholm, 8 Oct. (AKI) - Italian-American molecular geneticist Mario
Capecchi has scooped the 2007 Nobel Prize for Medicine, together with
two British geneticists, Martin Evans and Oliver Smithies.
The three scientists won the 1.5 million dollar prize for their
research on "principles for introducing specific gene modifications
in mice by the use of embryonic stem cells," Sweden's Karolinska
Institute announced on Monday.
Capecchi was born in Verona in 1937. He has spent most of his life in
the United States, where he is currently Howard Hughes Medical
Institute Investigator and Distinguished Professor of Human Genetics
and Biology at the University of Utah, Salt Lake City.
He is also a member of the US National Academy of Sciences (NAS)
whose members act as "advisers to the nation on science, engineering,
and medicine."
Evans, in his mid sixties, is credited with the discovery of
embryonic stem cells and for his work on the gene targeting
technique. He has been knighted for his contribution to genetics.
Smithies, the oldest of the three, is Excellence Professor of
Pathology and Laboratory Medicine at the University of North
Carolina. He was born in Britain in 1925.
The prize ceremony will take place on 10 December - the anniversary
of Alfred Nobel's death.
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StemCells subscribers may also be interested in these sites:
Children's Neurobiological Solutions
http://www.CNSfoundation.org/
Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123
The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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