Saturday, December 29, 2007

[StemCells] SCs clone pigs more efficiently for Xenotransplants

SKoreans claim to create cloned pigs through stem cells

SEOUL (AFP) — South Korean scientists said Thursday that they had
developed a more efficient way to produce cloned pigs suitable for
organ transplants for humans.

Unlike the traditional cloning method using somatic cells, the
scientists said they had used stem cells extracted from pigs' bone
marrow to obtain cloned embryos -- much improving the success rate.

The scientists wanted to clone smaller-than-normal pigs weighing
between 60-80 kilogrammes (132-176 pounds) when adult, since their
organs would be a similar size to human ones.

They said it was the first time such pigs had been cloned using stem
cells.

"This is a highly efficient method to produce cloned mini-pigs," said
Seong Hwan-Hoo, a senior researcher with the National Institute of
Animal Science.

Embryos cloned using somatic cells have only a one to five percent
chance of survival, the team said. Using stem cells, this can be
increased to 20 percent.

Four baby pigs cloned through stem cells were born on December 3. One
was killed for DNA analysis, one was crushed to death while feeding
and the remaining two are growing well.

"This technology will be useful to produce mini-pigs with modified
genes, whose organs may cause little resistance when transplanted
into human beings," Seong told AFP.

South Korea's bio-engineering industry suffered a setback after a
much-touted achievement by cloning expert Hwang Woo-Suk turned out to
have been faked.

Hwang, who is on trial for fraud, embezzlement, ethical breaches and
other charges, has been banned from research using human eggs after
his claims that he created the first human stem cells through cloning
were ruled to be bogus.
http://afp.google.com/article/ALeqM5i8OjtpekO51gT7eFTl9LEhDpbBYA

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StemCells subscribers may also be interested in these sites:

Children's Neurobiological Solutions
http://www.CNSfoundation.org/

Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123

The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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