Parthenogenesis: A Way of Fulfilling The Stem Cell Needs of 50% of
The Population - - And Without ethical Objections.
Redondo Beach, CA 90277 March 17 2008
By Dr. Hans J. Kugler, PhD
President
Tel:
310-540-0564.
International Academy of Anti-Aging Medicine (IAAM)(*).
With much admiration for the ground-breaking work at Boston
Children's Hospital (1), Kobe Univ. in Japan (2), SUMS Univ. in China
(3), Univ. of Milan, Italy (4), Univ. S. Florida, Tampa (5), Heinrich
Heine Univ., Germany (6), Michigan State Univ. (7), and many others:
We believe that, on the basis of available research data, the time is
right for IAAM Stem Cell Research, Dr. Hans J. Kugler, PhD, director,
to recommend that woman of child-bearing age give it serious
consideration to have a number of their egg cells collected and
stored (by a cryogenic facility) for possible future needs of stem
cells.
Today, when a child is born, parents have the choice of storing
umbilical chord blood (containing stem cells) for future needs of the
child. The same facilities could store egg cells. Even if it should
turn out that egg cells are not suited for making individual-specific
stem cells, these eggs are not wasted; they could be a blessing for
other people and are like money in the bank.
(*) IAAM. IAAM is a California 501-C-3 non-profit educational
corporation, located in Redondo Beach, CA. The IAAM Stem Cell
Research laboratory was founded because of the many delays in stem
cell research – legal, ethical, regulatory, political. Our goal:
making safe and person-specific stem cells (stem cells with DNA the
same as the recipient). Considering ourselves conservative, we feel
uncomfortable with the concept of harvesting stem cells from aborted
fetuses or from embryos from fertility clinics ( - - which will not
yield person-specific stem cells anyway). We find the Petri-dish
Nuclear Transfer, and the Parthenogenesis methods acceptable, and our
laboratory is set up for such work. We have been exploring
parthenogenesis – virgin birth (getting an egg cell to divide without
fertilization) – as a source of stem cells; this would not require a
nuclear transfer (it already contains only DNA from the donor), but
it would also bypass ethical objections. Furthermore, since there -
most likely - would be no ethical objections, manipulating such a
cell with DNA from a (male) skin cell, it should be possible to find
ways to yield stem cells for the other half of the population.
For a more complete list of references, including abstracts of the
papers quoted above, go to www.antiagingforme.
Monday; nothing to buy, free access), click on FREE eBooks, and then
on IAAM STEM CELL RESEARCH, Part IV.
Or: Request parthenogenesis reference list from
drkugler@roadrunner
(1) Differentiation potential of histocompatible parthenogenetic
embryonic stem cells.
Lengerke C, Kim K, Lerou P, Daley GQ
Division of Pediatric Hematology/Oncology
Boston, 300 Longwood Avenue, Boston, MA 02115, USA.
Ann N Y Acad Sci. 2007 Jun;1106:209-
(2) The maternal nucleolus is essential for early embryonic
development in mammals. Ogushi S, Palmieri C, Fulka H, Saitou M,
Miyano T, Fulka J Jr. Graduate School of Science and Technology, Kobe
University, Kobe 657-8501, Japan. ogushi@cdb.riken.
Feb 1;319(5863):
(3) Derivation of human embryonic stem cell lines from
parthenogenetic blastocysts. Main Q, YU Y, LI T, Wang L, Chen MJ,
Huang SZ, Zhou C, Zhou Q. 1Reproductive Medical Center, the First
Affiliated Hospital of SUMS University, Guangzhou 210029, China. Cell
Res. 2007 Dec;17(12):1008-
(4) Parthenotes as a source of embryonic stem cells.
Brevini TA, Gandolfi F
Laboratory of Biomedical Embryology, Centre for Stem Cell Research,
University of Milan, Milan, Italy. tiziana.brevini@
Cell Prolif. 2008 Feb;41 Suppl 1:20-30.
(5) Telomere lengthening early in development.
Lui L, Bailey SM, Okuka M, Munoz P, Li C, Zhou L, Wu C, Czerwiec E,
Sandler L, Seyfang A, Blasco MA, Keefe DL.
Laboratory for Reproductive Medicine, Department of Obstetrics and
Gynecology, University of South Florida College of Medicine, Tampa,
Florida 33612, USA. liutelom@yahoo.
Nat.Cell Biol. 2007 Dec;9(12):1436-
(6) Can artificial parthenogenesis sidestep ethical pitfalls in human
therapeutic cloning? An historical perspective.
Fangerau H.
Institute for the History of Medicine, Heinrich-Heine University
Düsseldorf, Universitaetsstrass
heiner.Fangerau@
5.
(7) Embryonic stem cells from parthenotes.
Cibelli JB, Cunniff K, Vrana KE.
Department of Animal Science, Michigan State University, East
Lansing, Michigan, USA.
Methods Enzymol. 2006;418:117-
Dr. Hans Kugler (drkugler@roadrunner
International Academy of Anti-Aging Medicine
Redondo Beach, CA 90277
Phone : 310-540-0564
Contact Dr. Hans Kugler
http://www.expertcl
Action=ContactExper
http://www.expertcl
Action=ReleaseDetai
«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»«¤»¥«¤»§«¤»¥«¤»§«¤»¥«
¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯
StemCells subscribers may also be interested in these sites:
Children's Neurobiological Solutions
http://www.CNSfoundation.org/
Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123
The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
____________________________________________
«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»«¤»¥«¤»§«¤»¥«¤»§«¤»¥«
¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯¯
Change settings via the Web (Yahoo! ID required)
Change settings via email: Switch delivery to Daily Digest | Switch format to Traditional
Visit Your Group | Yahoo! Groups Terms of Use | Unsubscribe
__,_._,___
No comments:
Post a Comment