Trial could 'recover' MS damage
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Last Modified: 27 Sep 2007
Source: PA News
A pioneering new treatment which could help thousands of multiple
sclerosis suffers "recover" from the incurable disease is being
trialled for the first time on a group of British patients.
They will be injected with bone marrow stem cells, which researchers
hope will repair damaged areas of the brain and spinal cord
and "reverse" their physical decline.
The trial - which is being carried out at Frenchay Hospital, near
Bristol - is believed to be the first time this type of authorised
therapy has been tested on patients anywhere in the world.
Around 85,000 people in the UK suffer from MS, which is a
degenerative disease of the central nervous system and can leave
patients wheelchair-bound and paralysed.
Previous studies have found some cells migrate to damaged areas in
the brain and spinal cord and are able to 'home in' on the damaged
areas.
Neil Scolding, professor of clinical neurosciences for North Bristol
NHS Trust, who is leading the trial, said he hoped the treatment
would offer a major breakthrough in treating the illness.
"We believe that bone marrow cells have the capability to repair
precisely the type of damage that we see in the brain and spinal cord
in MS. So by giving patients very large numbers of their own bone
marrow cells we hope that this will help stabilise the disease and
bring about some repair.
"That is the aim: to repair and recover and to try and reverse the
disease.
"It might not work first time round. We might need to refine the
technique, but at last we have started using it on patients, which is
very exciting."
The six patients - aged in their 30s to 50s - all suffer disabilities
as a result of their MS. The group will be closely monitored over the
next year and will undergo regular brain scans to see what impact the
treatment has on their disabilities.
http://www.channel4
er+ms+damage/
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StemCells subscribers may also be interested in these sites:
Children's Neurobiological Solutions
http://www.CNSfoundation.org/
Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123
The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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