Study: Stem cells may prevent amputations
by MT Bureau - January 22, 2008 - 0 comments
Evanston, Ill. -- Northwestern University researchers have launched
the first U.S. trial in which stem cells are used to grow new blood
vessels to prevent leg amputations.
Scientists are transplanting a purified form of subjects' own adult
stem cells into their legs that have severely blocked arteries. The
goal is to grow new small blood vessels and restore circulation.
The first two subjects in the 20-site national trial recently
underwent the stem cell transplant process at Northwestern Memorial
Hospital.
Scientists at the university's Feinberg School of Medicine who are
leading the study said severely blocked arteries in the leg and
sharply diminished blood flow can result in wounds that don't heal,
tissue breakdown and gangrene. That condition, called critical limb
ischemia, results in the amputation of more than 100,000 limbs
annually in the United States.
The research targets patients who have exhausted all other medical
options including angioplasty, stents and bypass surgery to repair
blocked circulation in their legs.
"They're at the end of the therapeutic road and they're ultimately
facing potential amputation," said Dr. Douglas Losordo, the study's
principal national investigator. "This is hopefully a way to help
them avoid that."
Copyright 2008 by United Press International.
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StemCells subscribers may also be interested in these sites:
Children's Neurobiological Solutions
http://www.CNSfoundation.org/
Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123
The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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