mucous membrane epithelial sheet transplant successful
PARIS — Surgeons have successfully performed an autologous
transplantation of oral mucous membrane epithelial sheet in corneas
with severe corneal damage, a speaker here said.
Carole Burillon, MD, presented first results of phase 1 and 2 trials
of the procedure for restoring corneal stem cells in patients with
bilateral stem cell deficit from corneal burns and Stevens-Johnson
syndrome at the French Society of Ophthalmology meeting.
The autologous epithelial oral mucosal stem cell transplantation was
first performed on seven patients in October 2007.
"The seven patients showed improvement of the principle criteria,
which were reduction of keratitic precipitates, suppression of ulcer
and regression of corneal neovascularization,
The only patient who had an adverse reaction was suffering from
Lyell's syndrome, according to Dr. Burillon.
Based on those results, Dr. Burillon and colleagues were able to
enroll five more patients in February.
http://www.osnsuper
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StemCells subscribers may also be interested in these sites:
Children's Neurobiological Solutions
http://www.CNSfoundation.org/
Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123
The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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