May 31 2008, 12:48 AM EST
New stem cell therapy may aid the repair of damaged brains
EUREKALERT
Contact: Sean Wagner
swagner@wiley.
781-388-8550
Wiley-Blackwell
According to some experts, newly born neuronal stem cells in the
adult brain may provide a therapy for brain injury. But if these stem
cells are to be utilized in this way, the process by which they are
created, neurogenesis, must be regulated.
A new study, led by Laurence Katz, Co-Director of the Carolina
Resuscitation Research Group at the University of the North Carolina
School of Medicine, suggests a way in which this might be achieved.
According to the research, neurogenesis can be regulated through
induced hypothermia. In rat subjects, a mild decrease in body
temperature was found to substantially decrease the proliferation of
newly-born neurons, a discovery that marks a major step forward for
the development of neuronal stem cell-based brain therapies.
Since the 1930s, brain damage from stroke, head injury, near drowning
and cardiac arrest was considered to be permanent because of a lack
of repair mechanisms like other parts of the body. However, discovery
of neuronal stem cells in the adult brain challenges that belief.
Many questions remain before we adequately understand how to control
these cells to repair a damaged brain, says Katz. However, the
findings represent an important step in demonstrating that these
cells can be controlled by simple external forces like hypothermia.
The presentation entitled Hypothermia Decreases Neurogenesis will be
given by Laurence Katz from The University of North Carolina School
of Medicine. This paper will be presented at the 2008 SAEM Annual
Meeting, Washington,D.
forum beginning at 10 a.m. in Virginia Rooms A&B of the Marriott
Wardman Park Hotel. Abstracts are published in Vol. 15, No. 5,
Supplement 1, May 2008 of Academic Emergency Medicine, the official
journal of the Society for Academic Emergency Medicine.
###
Press Room 2008 SAEM Annual Meeting, May 29-June 1, 2008,Washington,
D.C.
Location Park Tower Suite #8229
Chicago, IL
Tel: (202) 328-2000 (ask for the SAEM Registration Desk)
Fax: (202) 234-0015 (mark for attn of [Maryanne Greketis or Sandra
Rummel])
Contact Sean Wagner (swagner@wiley.
prior to or during the SAEM Annual Meeting. Dr. Katz can be reached
directly at lkatz@med.unc.
About The Society for Academic Emergency Medicine (www.saem.org)
The Society for Academic Emergency Medicine (SAEM) is a national non-
profit organization of over 6,000 academic emergency physicians,
emergency medicine residents and medical students. SAEM's mission is
to improve patient care by advancing research and education in
emergency medicine. SAEM's vision is to promote ready access to
quality emergency care for all patients, to advance emergency
medicine as an academic and clinical discipline, and to maintain the
highest professional standards as clinicians, teachers, and
researchers. The SAEM Annual Meeting attracts approximately 2,000
medical students, residents and academic emergency physicians. It
provides the largest forum for the presentation of original research
in the specialty of Emergency Medicine.
About Academic Emergency Medicine (www.aemj.org)
AEM is a peer-reviewed journal whose goal is to advance the science,
education, and clinical practice of emergency medicine, to serve as a
voice for the academic emergency medicine community, and to enhance
the goals and objectives of the Society for Academic Emergency
Medicine (SAEM). Members and non-members worldwide depend on this
journal for translational medicine relevant to emergency medicine, in
addition to clinical news, case studies and more.
About Wiley-Blackwell
Wiley-Blackwell was formed in February 2007 as a result of the
acquisition of Blackwell Publishing Ltd. by John Wiley & Sons, Inc.,
and its merger with Wileys Scientific, Technical, and Medical
business. Together, the companies have created a global publishing
business with deep strength in every major academic and professional
field. Wiley-Blackwell publishes approximately 1,400 scholarly peer-
reviewed journals and an extensive collection of books with global
appeal. For more information on Wiley-Blackwell, please visit
www.blackwellpublis
http://www.genengne
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StemCells subscribers may also be interested in these sites:
Children's Neurobiological Solutions
http://www.CNSfoundation.org/
Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123
The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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