Friday, May 9, 2008

[StemCells] Eggs from Stem Cells

Stem cells offer hope for 'delayed' menopauseAds By Google
Researchers from the University of Tennessee have developed early
stage human eggs have been developed from stem cells for the first
time that could that it could lead to the natural menopause being
delayed by up to 12 years.

According to BBC, the team led by Antonin Bukovsky took ovarian
surface epithelium (OSE) cells from the outside of the ovaries of
five women aged 39 to 52 and grew them in a lab for five to six days.
Some were exposed to a growth-stimulating oestrogen medium called
phenol red.

Cells cultured without phenol red differentiated into immature small
cells of various different types while the exposed ones completed the
first stage of the division needed to become mature human eggs,
capable of being fertilised and developing into an embryo.

They went on to become mature human eggs capable of being fertilised
and developing into an embryo. The team say the OSE cells can be
easily harvested from the surface of the ovaries, using a
laparoscope, a flexible telescope-like instrument.

They said the discovery could help those women with poor fertility or
who are set to go through an early menopause, who lack follicles in
their ovaries, to have a better chance of conceiving through IVF.

"Development of numerous mature oocytes (eggs) from adult ovarian
stem cells in vitro (in the laboratory) offers new strategies for the
egg preservation, IVF utilisation, and treatment of female
infertility," Bukovsky added.

http://www.hindustantimes.com/StoryPage/StoryPage.aspx?id=f16e6c00-
2bcd-4676-8efc-5fc3aaf855f6&ParentID=c410b9ae-ac6e-463e-a5ca-
c26a149c119b&&Headline=Stem+cells+offer+hope+for+'delayed'+menopause

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StemCells subscribers may also be interested in these sites:

Children's Neurobiological Solutions
http://www.CNSfoundation.org/

Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123

The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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