Thursday, April 3, 2008

[StemCells] India's SC-based drug for Crit. limb ischemia

Indian biotech's Eureka moments are here
April 3, 2008

Suresh (name changed), a farmer in Hoskote, Karnataka, was diagnosed
with a blood clot in his leg. The clot in the artery blocked oxygen
supply and left him in agony. But an injection formulated by
Bangalore-based Stempeutics in 2006 changed his life. The artery was
regenerated using stem cells extracted from his bone marrow. Today,
he is normal.

Srijani (name changed), 55, was undergoing cancer therapy in Delhi.
The drugs killed healthy cells with cancer cells. A new generation of
under-development drugs would target just cancer cells. Understanding
their effectiveness requires testing on humans, which is not allowed
anywhere in the world. Bangalore-based Cellworks came up with a
unique solution — computer simulation that predicts how a patient
would react to the drugs.

Cellworks and Stempeutics are just two of India's new biotechnology
start-ups that are making fairytales like these possible. Cellworks
designed the virtual patient, on whom `virtual medicine' can be
tested. Stempeutics works with stem cells, which help regenerate
critical body parts.

"We are aiming to create the medical equivalent of Google Maps — a
patient or illness that sits inside a computer instead of being
alive," said Taher Abbasi, who heads Cellworks. The software would
help pharma firms know early whether they are on the right track. New
medicines require almost 10 years to develop, and developers need to
know early whether they have the potential to work.

Stempeutics uses a type of stem cell found inside bone marrow to make
the drug for critical limb ischemia — what Suresh suffered from —
that will be available in India soon.
http://www.hindustantimes.com/StoryPage/StoryPage.aspx?id=ad9e15de-
10cc-488f-b3a4-
44e4381fa25a&MatchID1=4679&TeamID1=6&TeamID2=3&MatchType1=1&SeriesID1=
1179&MatchID2=4674&TeamID3=4&TeamID4=8&MatchType2=1&SeriesID2=1177&Pri
maryID=4679&Headline=Indian+biotech%e2%80%99s+Eureka+moments+are+here

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StemCells subscribers may also be interested in these sites:

Children's Neurobiological Solutions
http://www.CNSfoundation.org/

Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123

The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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